Hox proteins are conserved homeodomain transcription factors known to be crucial regulators Marvel - other of animal development.As transcription factors, the functions and modes of action (co-factors, target genes) of Hox proteins have been very well studied in a multitude of animal models.However, a handful of reports established that Hox protein
RNA pseudoknots are a kind of minimal RNA tertiary structural motifs, and their three-dimensional (3D) structures and stability play essential roles in a variety of biological functions.Therefore, to predict 3D structures and stability of RNA pseudoknots is essential for understanding their functions.In the work, we employed our previously develope
Non-specific back pain continues to be one Counter Height Stool of the leading causes of financial and economic costs in developed countries.The increasing popularity of interventional methods of pain treatment is linked to the high efficiency and rapid arresting of the disease symptoms.However, the use of invasive methods can be fraught with serio
The role of mountain uplift in the evolution of the global climate over geological times is controversial.At the heart of this debate is the capacity of rapid denudation to drive silicate weathering, which consumes CO2.Here we present the results of a 3-D model that couples erosion and weathering during mountain uplift, in which, for the first time